Mark Zuckerberg, the chief of Facebook, and his wife, Priscilla Chan, at the White House in September. They announced on Facebook the birth of their daughter, Max. Credit Molly Riley/Agence France-Presse — Getty Images

With their pledge to donate shares worth $45 billion, Mark Zuckerberg, chief executive of Facebook, and his wife, Priscilla Chan, have sent the world of philanthropy into a flurry of expectations.

The couple described broad goals for the money, which will be managed by a new organization, the Chan Zuckerberg Initiative. “Our initial areas of focus will be personalized learning, curing disease, connecting people and building strong communities,” they wrote.

We asked readers if they were in their position, what charities or causes would they support? The prompt drew hundreds of responses from around the world.

Click here to read a selection »